Can Ki-67 with 5.5% Be Better in Predicting Prognosis for Well Differentiated Pancreatic Neuroendocrine Tumors?

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Introduction: Pancreatic neuroendocrine tumors (NETs) are rare malignancies, Ki-67 is a cell proliferation marker that has been shown to have some utility in predicting prognosis of neuroendocrine tumors. However, the ideal grading method for G1/G2 remains controversial.

Aim(s): To study ki67 index in the role of predicting prognosis for patients(pts) with G1/G2 Pancreatic NETs.

Materials and methods: This was a retrospective study, the enrolled pts with grades G1 and G2 pancreatic NETs diagnosed at China-Japan Friendship Hospital from January 2012 to June 2018 were included. The follow-up deadline was June 2019. The diagnosis was based on the 2017 WHO endocrine organ tumor classification. The consensus of tumor pathological diagnosis was analyzed by SPSS 23.0 statistical software, cut-off value was calculated by ROC curve, and Kaplan-Meier method was used for univariate analysis to compare overall survival time.

Conference: 17th Annual ENETSConcerence (2020)

Presenting Author: Tan H

Authors: Yuan B, Chen Y, Zhang P, Wang X, Tan H,

Keywords: Pancreatic net, G1, G2, Ki-67, overall survival time,