Clinical Presentation and Prognosis of Patients with Medullary Thyroid Cancer

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Introduction: Medullary thyroid carcinoma (MTC) is a rare type of tumor that originates from parafollicular C-cells and accounts for 3–4% of all malignant thyroid neoplasms. MTC presents as sporadic (75–80%) or inherited tumors (20–25%). Hereditary MTC is part of multiple endocrine neoplasia type 2 (MEN2).

Aim(s): Aim of the study was to describe clinical presentation, prognosis and therapy of sporadic MTC patients.

Materials and methods: Sixty-seven patients (pts) with histologically confirmed MTC referred to ENETS Center of Excellence of Naples, Endocrinology Unity of Federico II University between 2010-2018 were evaluated. MEN-2-inherited MTC were excluded. Clinical-pathological data, therapy and survival were retrospectively reviewed.

Conference: 17th Annual ENETSConcerence (2020)

Presenting Author:

Authors: de Cicco F, Modica R, Barba L, Bottiglieri F, Minotta R,

Keywords: Medullary thyroid carcinoma, natural history, treatment, prognosis,