Clinical significance of interval imaging in patients with well-differentiated neuroendocrine neoplasms (NENs) receiving peptide receptor radionuclide therapy (PRRT)

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Introduction: PRRT is an effective therapy for advanced NENs with SSTR-avid disease, however, the role of interval imaging in between PRRT cycles and its benefit is unknown.

Aim(s): To investigate the correlation of radiographic response on interval imaging with response on first post-PRRT imaging.

Materials and methods: We analysed patient and treatment characteristics and radiographic responses among patients who received Lu-177-DOTATATE PRRT and underwent conventional interval imaging with CT or MRI. Response was classified as partial response (PR), stable disease (SD), progressive disease (PD) or mixed.

Conference:

Presenting Author:

Authors: Grewal U, Patel R, Chandasekharan C,

Keywords: Peptide receptor radionuclide therapy, interval imaging, neuroendocrine tumour,