Clinicopathological Features and Prognostic Analysis of 227 Cases with Well-Differentiated Gastric Neuroendocrine Tumors


Introduction: Gastric neuroendocrine neoplasms (g-NENs) are a group of rare tumors with a strong heterogeneity, subdivided as well-differentiated neuroendocrine tumors (NETs, type 1-3 g-NETs) and poorly-differentiated neuroendocrine carcinoma(NECs). WHO classification(2019) for digestive system tumours has carried out a new classification and grading criteria for NENs of the gastrointestinal tract recently, there is very few relevant clinical data based on this new classification, especially for gastric NETs(g-NETs).

Aim(s): To elucidated the prognostic role of the new classification of well-differentiated g-NETs

Materials and methods: A total of 227 cases with well differentiated NETs were identified in this study, including type 1 g-NETs (n = 143 ), type 2 g-NETs (n = 7), and type 3 g-NETs (n =77). Data were retrospectively collected and analyzed from four NEN centers in China with a median follow-up of 43 months(25-75 th percentile: 31-64).

Conference: 17th Annual ENETSConcerence (2020)

Presenting Author:

Authors: Li Y, Tan H, Jie C, Jie L, Pan Z,

Keywords: clinicopathological features, prognostic analysis, well-differentiated gastric neuroendocrine tumors, grade, type,

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