Comparable survival benefit of local excision versus radical resection for 10-20mm rectal neuroendocrine tumors

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Introduction: The prevalence of rectal neuroendocrine tumors (RNET) is constantly increasing. But the optimal surgical management for 10- to 20-mm RNET is still a matter of debate.

Aim(s): This study aimed to explore the optimal surgical approach for 10-20mm RNET by comparing the outcomes between local excision and radical resection.

Materials and methods: We extracted clinicopathological information of 10-20mm RNET from the Surveillance, Epidemiology, and End Results (SEER) database. The 1:2 propensity score matching (PSM) method was used to balance the imbalanced baseline covariates (P＜0.05) between the local excision group and radical resection group. A Cox proportional hazards model was used to identify the risk factors associated with cancer-specific survival (CSS) and overall survival (OS).

Conference:

Presenting Author: Chen Q

Authors: Chen Q, Chen J, Huang Z, Zhou J, Zhao H,

Keywords: rectal neuroendocrine tumor, surgery, prognosis, SEER,