Comparison between Tang and WHO 5th Edition Grade Classification for Goblet Cell Adenocarcinomas


Introduction: Appendiceal GCAs (previously Goblet Cell Carcinoids) are composed of cells with secretory phenotypes. Several grading systems to predict behaviour are available (e.g.Tang). The latest WHO 5th edition adopted a grading system similar to colon adenocarcinomas.

Aim(s): To compare latest WHO and Tang grading systems.

Materials and methods: Data from patients (pts) with GCAs classified and graded according to both Tang and WHO systems seen at The Christie (1999 to 2014) were retrospectively analysed. McNemar and McNemar-Bowker test were used to study data asymmetry for comparing both classifications. Log-rank test and Kaplan-Meier (KM) method was used for overall survival (OS) analyses.

Conference: 17th Annual ENETSConcerence (2020)

Presenting Author:

Authors: Barriuso J, Nonaka D, Nagaraju R, Shenjere P, Lamarca A,

Keywords: goblet cell adenocarcinomas, tang, who grade,

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