Contrast-Enhanced Ultrasonography (CEUS) Reliably Predicts Tumor Progression in Pancreatic Neuroendocrine Tumors


Introduction: Neuroendocrine tumors (NETs) exhibit a typical vascular pattern in the arterial phase on CEUS. The role of CEUS in the prognostic evaluation of pancreatic NET (pNET) has been poorly investigated.

Aim(s): To prospectively investigate the prognostic role of CEUS in pts with pNET.

Materials and methods: Forty-seven pts with pNET underwent CEUS at the time of diagnosis. Twenty-five were non-functioning and 22 functioning pNETs. Multiple liver metastases (LMs) were in all 25 pts with non-functioning pNETs and in one with functioning pNET. Ki-67 index was available in 33/47 pts. Tumor progression was evaluated by using contrast-enhanced CT performed at 6- and 12-month follow-up and was based on Recist criteria.

Conference: 10th Annual ENETSConcerence (2013)

Presenting Author: Del Prete M

Authors: Del Prete M, Di Sarno A, Ramundo V, Marciello F, Marotta V,

Keywords: pancreatic neuroendocrine tumors, CEUS, contrast enhancement, prognosis,

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