Diagnostic Accuracy of F-18-DOPA PET or PET/CT in Neuroendocrine Tumors: A Meta-Analysis

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Introduction: A specific feature of NETs is amine precursor uptake and decarboxylation; this is the rationale for using PET with F-18-DOPA, a cathecholamine precursor, in diagnosis of NETs.

Aim(s): To meta-analyze published data about the diagnostic accuracy of F-18-DOPA PET in patients with NETs.

Materials and methods: A comprehensive literature search of studies about F-18-DOPA PET or PET/CT in patients with proven or suspected NETs was performed in PubMed/MEDLINE, Embase and Scopus databases. Pooled sensitivity (SS) and specificity (SP) on a patient-based analysis and area under the ROC curve were calculated.

Conference: 10th Annual ENETSConcerence (2013)

Presenting Author: Treglia G

Authors: Muoio B, Treglia G, Rufini V,

Keywords: PET, PET/CT, F-18-DOPA, neuroendocrine tumors,