Disease-specific mortality in a single-center cohort of 427 patients with carcinoid syndrome

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Introduction: The carcinoid syndrome (CS), the most prevalent hormonal syndrome in patients with a neuroendocrine tumor (NET), is associated with impaired survival. Due to the biological behaviour of NET and overall improvement in survival rates, patients with CS may not succumb to their disease. However, the contribution of NET-specific death in these patients is currently unknown.

Aim(s): To evaluate the causes of death in patients with CS and to determine overall survival (OS) as well as prognostic factors.

Materials and methods: Patients with CS treated between 1995 and 2021 at our ENETS Center of Excellence were retrospectively included for analysis. Kaplan-Meier curves and log-rank tests were used to perform a survival analysis and a Cox proportional hazards model was used to calculate mortality hazard ratios.

Conference:

Presenting Author: Maas C

Authors: Maas C, Mulders M, Feelders R, de Herder W, Hofland J,

Keywords: carcinoid syndrome, neuroendocrine tumor, prognosis, survival analysis,