Efficacy of the Combination of Capecitabine and Temozolomide in Patients with Advanced Pulmonary Carcinoid Tumours

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Introduction: Limited treatment options exist for patients (pts) with advanced pulmonary carcinoids (PC). Capecitabine-temozolomide (CAPTEM) has demonstrated significant efficacy in pts with pancreatic neuroendocrine tumours. However, its role in PC remains unexplored.

Aim(s): The aim of this study was to examine the efficacy of CAPTEM in advanced PC.

Materials and methods: Pts were treated with capecitabine 750mg/m2 BD day1-14 and temozolomide 200mg/m2 OD day10-14 of a 4-week cycle up to maximum of 6 cycles. All pts were treated at the Christie NHS Hospital from 3/2014 to 11/2015.

Conference: 13th Annual ENETSConcerence (2016)

Presenting Author: Papaxoinis G

Authors: Papaxoinis G, McCallum L, Nasralla M, Nonaka D, Mansoor W,

Keywords: pulmonary carcinoids, capecitabine, temozolomide,