Elevated inflammatory markers are associated with poor survival after surgery for pancreatic and small intestine neuroendocrine tumors

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Introduction: Gastroenteropancreatic neuroendocrine tumors (GEP-NET) are a heterogenous group of neoplasms. The only curative treatment is surgery. However, predictors of survival after surgery are still missing.

Aim(s): The aim of this study is to evaluate inflammatory markers (IM) as prognostic factors in GEP-NET patients.

Materials and methods: We examined the influence of inflammatory markers (CRP>20, fibrinogen>4) in 178 patients, 120 patients with pancreatic neuroendocrine tumors (pNET) and 58 with small intestine neuroendocrine tumors (siNET) on overall survival (OS) and recurrence free survival (RFS) in a single-center cohort study.

Conference:

Presenting Author:

Authors: Amin T, Kailani S, Fründt T, Viol F, Stripling J,

Keywords: Neuroendocrine tumor, inflammatory marker, GEP-NET, overall survival,