Expanding the WHO 2017 Classification to Gastrointestinal Tumors: Real-World Data from the R-GETNE Registry

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Introduction: The update of the WHO 2017 classification of pancreatic neuroendocrine tumors (NETs) introduces the distinction between NET & NEC G3, based on histological differentiation. However, little is known about the possibility of extending this concept to non-pancreatic NETs.

Aim(s): This analysis sought to assess the extension of the WHO 2017 classification to non-pancreatic NETs.

Materials and methods: Patients come from the R-GETNE registry. Survival was performed using Kaplan-Meier method. The additive effect of histological differentiation (well vs. poorly differentiated) and the Ki-67% index were evaluated by Cox regression, adjusted for confounding covariates (age, sex, TNM), and stratified by tumor location.

Conference: 15th Annual ENETSConcerence (2018)

Presenting Author:

Authors: Carmona-Bayonas A, Jimenez-Fonseca P, Castaño A, Capdevila J, Benavent M,

Keywords: WHO classification, NET G3, NEC G3, non-pancreatic NET, poorly differentiated,