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FDG-PET is Superior to WHO Grading in Predicting Overall Survival of Patients with Neuroendocrine Tumors: A Prospective Study of 172 Patients
Introduction: Accurate grading of patients with neuroendocrine tumors (NETs) is essential for risk stratification and optimal choice of therapy. Currently, WHO grading is based on histo-pathologically assessed degree of tumor proliferation.
Aim(s): To assess the prognostic value of FDG-PET imaging for risk stratification of NETs and compare it with WHO grading.
Materials and methods: We conducted a prospective, single-center cohort study evaluating the prognostic value of FDG-PET imaging and compared it to the current WHO grading. Patients (n = 172) of all grades and with histologically confirmed NETs of gastroenteropancreatic or pulmonary origin were enrolled. The primary end point was overall survival (OS). Progression-free survival (PFS) was a secondary end point.
Conference: 14th Annual ENETSConcerence (2017)
Presenting Author: Kjaer A
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