FOLFOX Chemotherapy: Efficacy and Tolerability in Advanced Digestive Neuroendocrine Neoplasms (NENs)


Introduction: FOLFOX has been poorly investigated in digestive NEN (DNENs), mostly in small cohorts.

Aim(s): To analyze efficacy, predictive factors of response and tolerability of FOLFOX in a consecutive series of advanced DNENs.

Materials and methods: Retrospective analysis of patients (pts) receiving FOLFOX IV in 2005-2015, with at least 3-mos follow-up. Objective response (OR) and progression-free survival (PFS) were assessed; prognostic factors analyzed by Cox-regression model.

Conference: 13th Annual ENETSConcerence (2016)

Presenting Author:

Authors: Dal Buono A, Merola E, Delle Fave G, Wiedenmann B, Pavel M,

Keywords: FOLFOX, tolerability, tumor response.,

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