Gastric metaplasia and duodenal neuroendocrine neoplasms: True causality or simple coincidence?

#3374

Introduction: Duodenal neuroendocrine neoplasms (dNENs) are heterogeneous tumors, whose natural history is poorly known. Duodenal gastric metaplasia (DGM) is considered to be a precancerous lesion which is generally related to chronic inflammation as first sign. No data are available regarding its possible role as a risk factors for dNEN occurrence.

Aim(s): To assess the prevalence of DGM in a cohort of histologically confirmed dNEN.

Materials and methods: Subgroup analysis of a retrospective study including all consecutive patients with dNEN, who underwent surgical resection between 2000-2019 and observed at eight Italian tertiary referral centers.

Conference:

Presenting Author: Rossi R

Authors: Rossi R, Milanetto A, Andreasi V, Campana D, Coppa J,

Keywords: duodenal neuroendocrine neoplasm, gastric metaplasia,