Gender and metastatic burden as preoperative predictors of disease progression in patients undergoing surgery for pancreatic neuroendocrine tumours with liver metastases

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Introduction: Pancreatic neuroendocrine tumour liver metastases (PanNET LM) are traditionally classified into three types based on their distribution. Surgery is generally considered for patients with type I/II LM, while those with type III LM are typically regarded as unresectable. However, type III PanNET LM encompass a wide range of clinical scenarios, some of which may allow surgical resection in selected cases.

Aim(s): To identify preoperative predictors of progression-free survival (PFS) following primary tumour resection in patients with M1 (liver) PanNETs.

Materials and methods: Consecutive patients with PanNETs LM who underwent primary tumour resection at the San Raffaele Hospital (2010-2023) were included.

Conference:

Presenting Author: Andreasi V

Authors: Andreasi V, Partelli S, Battistella A, Muffatti F, Tamburrino D,

Keywords: Pan NET, neuroendocrine, liver metastasis, surgery, gender, progression,