Genomic Landscape of Neuroendocrine Neoplasms from Gastrointestinal Tract, Pancreas, Lung, Rare and Unknown Primary Locations

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Introduction: There are still few large-scale sequencing data to depict the genomic landscape of neuroendocrine neoplasms (NEN).

Aim(s): To investigate the genomic characteristics and their clinical significance in NEN.

Materials and methods: This study of next-generation sequencing included patients with gastrointestinal neuroendocrine tumor (GI-NET), pancreatic NET (panNET), colorectal neuroendocrine carcinoma (CR-NEC), lung-NET, lung-NEC, prostate-NEC, rare-NET, NET of unknown primary (NET, NOS) and NEC of unknown primary (NEC, NOS) retrieved from AACR GENIE Database. Survival data was collected from cBioPortal.

Conference: 17th Annual ENETSConcerence (2020)

Presenting Author: Chen L

Authors: Chen L, Liu M, Zhang Y, Guo Y, Chen M,

Keywords: Genomics, neuroendocrine neoplasm, survival,