Incidence of psychiatric illness in patients with neuroendocrine tumors (NET): A comparative population-based analysis

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Introduction: Diversion of tryptophan to tumoral hormonal production has been suggested to result in increased prevalence of psychiatric illnesses (PI) in neuroendocrine tumors (NET), but such data are limited to case reports.

Aim(s): We measured the occurrence of PI after NET diagnosis and compared it to matched colon cancer (CC) cases.

Materials and methods: We linked population-based healthcare data to match adults with NET 1:1 to CC (2000-2019). PI was defined by mental health diagnoses (depression, psychosis, anxiety, schizophrenia) and mental health use after cancer diagnosis and categorized as severe, other, and none. Cumulative incidence functions accounted for death as a competing risk.

Conference: 18th Annual ENETS Concerence (2021)

Presenting Author: Hallet J

Authors: Hallet J, Isenberg-Grzeda E, Law C, Zuk V, Sohail S,

Keywords: neuroendocrine, psychiatry, mental health, prognosis,