Intra-arterial Peptide Receptor Radionuclide Therapy in a Filipino male with predominantly hepatic metastasis in a known primary pancreatic neuroendocrine tumor

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Introduction: Peptide Receptor Radionuclide Therapy (PRRT) has shown positive clinical outcomes in somatostatin receptor (SSTR) overexpressing positive well-differentiated neuroendocrine tumors in combination with somatostatin analogue therapy. A noted decreased progression-free survivability in the use of PRRT has been noted in larger lesions (>3cm).

Aim(s): The paper highlights the challenge associated with conventional intravenous administration of PPRT, proposing that altering the mode of administration to intra-arterial may enhance specificity in targeting tumor cells, especially in tumors with bulky lesions.

Materials and methods: This is a prospective case report study of the first documented intra-arterial PRRT in the Philippines. Consent was secured from the patient. Data collection was approved by the Institutional Review Board (IRB).

Conference:

Presenting Author: Azarraga C

Authors: Azarraga C, Leogardo D, Bandong I, Bautista-Peñalosa P,

Keywords: neuroendocrine, PRRT, intra-arterial, bulky,