Leak rates in pancreatico-duodenectomy procedures in pancreatic NETs compared to pancreatic ductal adenocarcinoma resections

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Introduction: Pancreatic resection for Neuroendocrine tumor is associated with a higher risk of anastomotic leak and post-operative pancreatic fistula (POPF).

Aim(s): The aim of this study was to compare POPF rate after Whipple’s operation for neuroendocrine tumor (NET) versus pancreatic ductal adenocarcinoma (PDAC).

Materials and methods: We conducted a retrospective case control analysis of a prospectively maintained database. Patients who underwent pancreatico-duodenectomy for NET and PDAC over a 10 year period at our institution were included in the study. Drain amylase levels on day 3 and day 5 were compared in the two groups by Mann-Whitney U test with p<0.05 considered a significant result. The definition of pancreatic fistula as defined by the International Study Group of Pancreatic Fistula was used.

Conference:

Presenting Author: Kalepu J

Authors: Kalepu J, Sundaravadanan S, Pike T, Karavias D, Hamady Z,

Keywords: Pancreatic resection, Whipple, pancreatic fistula, drain amylase,