Liver and Liver-Pancreastransplantation in the Two-stage Treatment of Liver Metastasized Neuroendocrine Tumors of the Pancreas: About Three Cases

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Introduction: Although liver transplantation is a valid option in the treatment of metastasized neuroendocrine tumors, it is not promoted because of a donor organ shortage and disappointing results in older series.

Aim(s): The key point for success in transplanting these patients lies in their selection. We will discuss the results of three patients with five-year follow up.

Materials and methods: Two patients with MEN1 syndrome and one patient with a somatostatinoma underwent pancreatectomy to treat the primary tumor site. Diffuse liver metastases, not suitable for hepatic resection, were diagnosed. In a second step, liver or liver-pancreas-transplantation was performed to treat the liver metastases. All patients were young (35, 40 and 44 years).

Conference: 8th Annual ENETSConcerence (2011)

Presenting Author:

Authors: Roeyen G, Chapelle T, De Greef K, Francque S, Michielsen P,

Keywords: livertransplantation, neuroendocrine tumor, selection criteria,

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