Management of Insulinomas: Perioperative and Long-term Outcomes Following Enucleations and Pancreatic Resections in 198 Patients

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Introduction: Enucleation represents the procedure of choice for the treatment of insulinomas. Considering the site and the number of lesions, however, formal pancreatic resection may be necessary.

Aim(s): To analyze perioperative and long-term outcomes after enucleation/pancreatic resections for insulinomas at two referral centers between 1990-2008.

Materials and methods: One-hundred and ninety-eight patients (116 females, median age 47.5 years) with symptomatic insulinoma were identified. 5.5% had MEN-1 syndrome. Surgical procedures included 106 enucleations (53.5%) and 92 pancreatic resections. There were no blind resections. Median FU was 65 months. Insulinomas were classified according to the 2000 and 2010 WHO PETs classifications.

Conference: 8th Annual ENETSConcerence (2011)

Presenting Author:

Authors: Boninsegna L, Zerbi A, Crippa S, Bettini R, Capitanio V,

Keywords: insulinoma, enucleation, pancreatic resection, tumor recurrence, diabetes, exocrine insufficiency,

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