Management of Multiple Endocrine Neoplasia Type 1 in Patients with Pancreatic Neuroendocrine Tumors
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Introduction: Screening for MEN-1 is an integral part of examination of patients with pNETs because revelation of this hereditary pathology radically influences tactics of treatment.
Aim(s): To analyze management of MEN-1
Materials and methods: Data on 46 patients (m-10, w-36) with MEN 1 syndrome was analyzed. In this group of patients we revealed pituitary adenomas in 59 % (N=27), primary hyperparathyroidism in 78 % (N=36) and pNETs in 94 % (N=43). There were 39 insulinomas, 7 nonfunctioning tumors, 4 gastrinomas and 2 glucagonomas. We used clinical, hormonal and a complex of imaging procedures of the pituitary, parathyroid and pancreas, supplemented by arterial stimulated venous blood sampling.
Conference:
Presenting Author:
Authors: Vasiliev I, Egorov A, Musaev G, Kondrashin A, Gurevich L,
Keywords: MEN-1 syndrome, pancreatic neuroendocrine tumor,
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