Mixed neuroendocrine non-neuroendocrine neoplasm associated with gastric autoimmunity: A clinicopathological analysis of two cases

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Introduction: Two cases of mixed neuroendocrine tumour - gastric adenocarcinoma were found in patients with autoimmune atrophic gastritis. Both components expressed synaptophysin, initially suggesting a neuroendocrine tumour diagnosis. However, further examination confirmed the presence of gastric adenocarcinoma of fundic gland type.

Aim(s): This study aims to analyse the rare MiNET-GAFG from a clinicopathological perspective, expanding understanding of AAG-related gastric tumours while improving pathological diagnosis of NET and GA-FG.

Materials and methods: Clinical data and pathological information were collected for two confirmed cases of MiNET-GAFG patients diagnosed in the Department of Pathology at Fudan University Cancer Hospital.

Conference:

Presenting Author:

Authors: Huang D, Chen X, Chu J, Ma M,

Keywords: Mixed neuroendocrine tumour, autoimmune atrophic gastritis, gastric adenocarcinoma of fundic gland type,