Natural History of Resectable Large Cell Neuroendocrine Carcinoma of the Lung

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Introduction: Lung large cell neuroendocrine carcinomas (LCNEC) are rare poorly differentiated carcinoma. Their natural history after surgery has been seldom studied.

Aim(s): To determine the disease-free survival (DFS), overall survival (OS) of sporadic, resectable (R0), non-metastatic lung LCNEC.

Materials and methods: This retrospective study involved 36 consecutive patients surgically treated between 1998-2008 for LCNEC in two Italian and French expert networks . Slides were reviewed by two expert pathologists to validate the definition of LCNEC (WHO 2004)

Conference: 10th Annual ENETSConcerence (2013)

Presenting Author:

Authors: Marciello F, Mercier O, Papotti M, Filosso P, De Latour B,

Keywords: lung neuroendocrine carcinoma, surgery, prognosis,