Neuroendocrine tumors in young adult patients - Epidemiological profile, clinical aspects and prognostic factors

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Introduction: Neuroendocrine tumors (NETs) comprise a rare disease. However, an increase in the number of cases in young-onset (18-40 years old) NETs (YONET) has been observed in our clinical practice. The data about YONETs profile are scarce.

Aim(s): To assess the frequency and clinical aspects of YONET in comparison to late-onset (>40 years old) NETs (LONET).

Materials and methods: A retrospective analysis of consecutive pts diagnosed with gastroenteropancreatic NETs treated from 2010 to 2018 at AC Camargo Cancer Center, Brazil. Descriptive analysis was used to summarize pts characteristics. Differences between groups were assessed by the chi-square test, and Kaplan-Meier was used to estimate progression free survival (PFS) and overall survival (OS) among the metastatic pts. Prognostic factors for PFS were assessed using Cox regression analysis. A p value<0.05 was significant.

Conference: 18th Annual ENETS Concerence (2021)

Presenting Author: Zanco Fogassa C

Authors: Fogassa C, Camandaroba M, Tanaka H, Felismino T, Riechelmann R,

Keywords: young-onset NETs, NET, gastroenteropancreatic NETs,