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Novel Symptoms and Therapy of Multiple Endocrine Neoplasia Type 1
Introduction: MEN1 is a rare autosomal inherited disease with hallmark of hyperparathyroidism, duodenopancreatic NENs and pituitary tumor.
Aim(s): To introduce a case with scarce symptom and treatment.
Materials and methods: A 53-year-old man underwent a chief complaint of epigastric discomfort accompanied by intermittent diarrhea with loose stools for 3-4 times per day for about 17 years. Then, he was treated with omeprazole which could effectively alleviate these symptoms. Last year, he got an endoscopy which showed thicken gastric wall with multiple polypoid eminence lesions (0.4-0.8cm in diameter) in the fundus and body of stomach. Moreover, there seems to be 2 small superficial lesions (0.5cm in diameter) in bulbus of the duodenum. EUS showed a homogenous mass (2.1*1.1cm) behind the pancreatic head. He got high level of PTH, calcium, gastrin, CgA.Somatostatin receptor scintigraphy with 68gallium revealed abnormal activity in epigastric region and left adrenal. Ultimately, we performed an laparoscopic and gastroscopic cooperative surgery (LGCS) for him.
Conference: 17th Annual ENETSConcerence (2020)
Presenting Author: bai J
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