Outcome of endoscopic submucosal dissection for rectal neuroendocrine neoplasms – A multicentre study

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Introduction: Recent guidelines recommend advanced endoscopic resection techniques, such as Endoscopic Submucosal Dissection (ESD), for the treatment of rectal neuroendocrine neoplasms (R-NENs) under 15mm due to high rate of positive margins at Endoscopic Mucosal Resection (EMR).

Aim(s): Data for supporting ESD on R-NENs are scarce. We retrospectively ruled in a western cohort of patients who had ESD for R-NENs and a post ESD endoscopic follow-up to evaluate its efficacy.

Materials and methods: Patients from eight western international tertiary referral centres were enrolled in the study. Adverse events, R1 rate and recurrences were analysed. Baseline demographics, as well as tumor characteristics and peri and post procedural adverse events were recorded. Given the retrospective nature of the study, follow up endoscopic time was not standardized.

Conference:

Presenting Author: Rimondi A

Authors: Rimondi A, Despott E, Lemmers A, Chacchi-Cahuin R, Lazaridis N,

Keywords: ESD, R-NENs, endoscopy,