Palliative Surgery in Advanced Small Intestinal Neuroendocrine Tumors


Introduction: Small intestinal neuroendocrine tumours (SI-NETs) are known to develop mesenteric metastasis and fibrosis. Since this can induce intestinal obstruction, edema and ischaemia, prophylactic palliative resection of the primary tumour and mesenteric mass is often recommended in case of advanced disease but the evidence is disputable.

Aim(s): We performed the largest retrospective study so far to assess the effect of prophylactic palliative surgery in advanced SI-NETs.

Materials and methods: A retrospective analysis of 538 patients with proven SI-NETs ENETS stage III or IV disease at diagnosis and available CT-imaging was performed. Clinical characteristics as well as the effect of abdominal surgery on overall survival were assessed.

Conference: 15th Annual ENETSConcerence (2018)

Presenting Author: Blazevic A

Authors: Blazevic A, Zandee W, Franssen G, Hofland J, Van Velthuysen M,

Keywords: Small intestinal neuroendocrine tumors, Palliative surgery, Prognosis,

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