Pattern of Disease Recurrence and Treatment after Radical Surgery for Nonfunctioning Pancreatic Neuroendocrine Tumors (NF-PanNET)


Introduction: The risk of recurrence after radical surgery performed for pancreatic neuroendocrine tumors (PanNET) is reported between 10 and 30%. Nowadays, no adjuvant therapy is recommended for these patients and specific treatments are offered only when recurrence occurs. Nevertheless, among the available systemic and locoregional treatments, there are no specific recommendations on which the best option could be for treating recurrent disease.

Aim(s): Aim of the present study was to evaluate the pattern of recurrence after radical surgery for nonfunctioning (NF)-PanNET and to analyze the impact of treatment on disease progression.

Materials and methods: All the patients (n=44) submitted to curative surgery for sporadic, well-differentiated, NF-PanNET at two Italian centers between 2001 and 2018, with evidence of disease recurrence during follow-up, were included.

Conference: 17th Annual ENETSConcerence (2020)

Presenting Author: Andreasi V

Authors: Andreasi V, Partelli S, Landoni L, Nessi C, Muffatti F,

Keywords: pancreatic neuroendocrine tumors, recurrence, surgery, locoregional treatment, systemic treatment,

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