Predictive value of pepsinogen I and I/II ratio for diagnosing autoimmune gastritis

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Introduction: Autoimmune gastritis (AIG) is sometimes difficult to diagnose.

Aim(s): To evaluate the predictive value of pepsinogen I (PGI) and I/II ratio as a non-invasive screening test for AIG.

Materials and methods: Retrospective analysis of 229 patients diagnosed with AIG and 189 patients with H. pylori associated atrophic gastritis as control group at Beijing Friendship Hospital 2020-2023. All patients underwent serological tests of fast gastrin-17, pepsinogen I/II, anti-H. pylori antibody, gastroscope and biopsy histology. The study was registered in Chinese Clinical Trial Registry (ChiCTR2200062001).

Conference:

Presenting Author:

Authors: Hu H, Chen C, Zhang Q, Li P,

Keywords: autoimmune gastritis, pepsinogen 1, pepsinogen 1/2 ratio, gastrin,