Preoperative evaluation of tumour border using radiomics and its surgical guidance in pancreatic neuroendocrine tumours

#4523

Introduction: Pancreatic neuroendocrine tumours are a heterogeneous group of tumours originating from peptidergic neurons and neuroendocrine cells with variable survival outcomes. Surgical resection is the mainstay of treatment. However, there is an ambiguous insight into the real need to execute the standard surgery in small pancreatic neuroendocrine tumours. The tumour border is a powerful determinant of survival prognosis in many tumours and is often used as a safety guarantee for parenchyma-sparing resections. However, there are no studies evaluating tumour border with or without preoperative imaging in pNETs.

Aim(s): The study attempted to use preoperative CT-based radiomics to predict tumour boundaries and thus to know the operative choice.

Materials and methods: Patients with pNETs who underwent the first surgical resection at the Affiliated Cancer Hospital of Fudan University from 2012-2023 (n=578) were selected with approval of the Institutional Review Board and patient consent was obtained. 377 patients who had undergone multi-phase contrast-enhanced CT were enrolled in the radiomics analysis.

Conference:

Presenting Author: Wang Y

Authors: Wang Y, Gu W, Tang W, Huang D, Zhang W,

Keywords: pancreatic neuroendocrine tumour, border, computed tomography, enucleation, radiomics,