Primary Hepatic Neuroendocrine Carcinomas Treated with a Combination of Cisplatin and Etoposide as First-Line Chemotherapy: Two Case Reports

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Introduction: Because primary hepatic neuroendocrine carcinoma (PHNEC) is extremely rare, a standard regimen has not yet been established. However, the combination of etoposide and cisplatin (EP) has been widely used to treat PHNEC.

Aim(s): We report two cases of PHNEC treated with EP and compare the efficacy of the EP regimen for PHNEC and pancreatic NEC (pNEC).

Materials and methods: We retrospectively analyzed the medical records of patients diagnosed with PHNEC and pNEC during January 2007–November 2012.

Conference: 10th Annual ENETSConcerence (2013)

Presenting Author:

Authors: Nakazuru S, Iwasaki R, Tamura T, Iwasaki T, Hasegawa H,

Keywords: liver, neuroendocrine carcinoma, chemotherapy,