Primary Neuroendocrine Tumor of the Parathyroid

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Introduction: Parathyroids are derived from third and fourth branchial pouches and neuroendocrine C-cells originate for neighboring fifth branchial pouch. A close ontogenic relation between these embryonal pouches is illustrated in DiGeorge syndrome wherein there is an absence of parathyroid glands and C-cells. It is not known for certain if normal parathyroids contain NE cells. However, NETs of the parathyroid have been reported in two other cases (Medline search: 1966-2011).

Aim(s): We report a third case along with treatment given and follow-up course.

Materials and methods: A 61-year-old woman presented with respiratory distress. She had outside surgery for an 8 cm "parathyroid tumor," adherent to strap muscles and trachea. Our Investigations: Serial serum Ca++,PTH, Vitamin D, ALKptase, albumin. Histopathology, immunostains, US/CT Neck, CT Chest, PET-CT, Bone scan.

Conference: 9th Annual ENETSConcerence (2012)

Presenting Author:

Authors: Ahmed M,

Keywords: parathyroid NET,