Prognostic Factors of Pulmonary Carcinoid Tumors
Introduction: Pulmonary carcinoids (PC) are rare malignant neoplasms that account for approximately 1% of all lung cancers. PCs are classified by histological criteria as either typical (TC) or atypical (AC). Histological subtype is the most studied prognostic factor.
Aim(s): The aim of this study was to evaluate if other tissue or clinical features associated with patient outcomes.
Materials and methods: We retrospectively reviewed clinical records of 133 PC patients who were surgically treated at our institution between 1990 and 2013. Tissue specimens were re-evaluated, processed into tissue microarray format and stained immunohistochemically with serotonin, calcitonin, adrenocorticotropic hormone (ACTH), thyroid transcription factor-1 (TTF-1) and Ki-67. Survival analyses with Cox regression and Kaplan-Meier were performed.
Conference: 15th Annual ENETSConcerence (2018)
Presenting Author: Vesterinen T
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