Rare diagnosis of intrapancreatic accessory spleen mimicking PanNET

#4614

Introduction: A 44-year-old woman with hypertension and an autoimmune thyroid disease. With a positive family history of pancreatic and oesophageal cancer. Referred to our clinic for an incidental finding of a tumour in the tail of the pancreas on abdominal ultrasound by a surgeon.

Aim(s): A contrast-enhanced CT scan of the abdomen was performed, where a hyper-enhancing lesion measuring 12x12mm was observed in the tail of the pancreas in the arterial phase. The scans were compared with an MRI from nine years ago, where the lesion was not present.

Materials and methods: An endosonography was added, revealing a slightly hypoechoic, homogeneous, well-defined lesion measuring 12.1mm in diameter with vascularisation present in CFI. A fine needle biopsy (FNB) was performed, yielding a borderline positive histological finding for PanNET, with acinar to subtly trabecular structures present. Immunohistochemically, CK7+ and CD56+ were positive, with inconclusive expression of CD56 in the "trabecular structures" along with minimal proliferative activity (Ki-67).

Conference:

Presenting Author: Uhrík P

Authors: Uhrík P, Nosakova L, Vojtko M, Bánovčin P,

Keywords: fine needle biopsy, accessory spleen, Neuroendocrine tumour,