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Risk Factors for Survival from Neuroendocrine Neoplasia with Unknown Primary Tumor Site


Introduction: Neuroendocrine neoplasia (NEN) with unknown primary site (NEN-CUP) may have a poor prognosis. We evaluated the clinical presentation, therapy, outcome, and risk factors for adverse outcomes in patients with NEN-CUP.

Aim(s): Role of surgery in NEN-CUP

Materials and methods: In 243 patients who had NEN, a retrospective review was performed in 38 patients who had NEN-CUP tumors. The 38 patients who had NEN-CUP were evaluated in 3 groups: group 1 (surgery; primary tumor detected; n=10); group 2 (surgery; no primary tumor detected; n=10); and group 3 (no surgery; n=18). Risk factors were evaluated with univariate and multivariate analysis.

Conference: 12th Annual ENETSConcerence (2015)

Presenting Author: Begum N

Authors: Begum N, Wellner U, Thorns C, Hoffmann M, Bürk C,

Keywords: outcome, NEN-CUP, surgery, survival,

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