Secondary primary cancers and survival among neuroendocrine tumor patients

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Introduction: Higher rates of second cancer (SC) are suggested for patients with neuroendocrine tumors (NET), but data on SC are scare and their impact on outcomes is unknown.

Aim(s): Evaluate the association between SC after NET diagnosis and survival.

Materials and methods: We identified gastrointestinal (GI), pancreatic, and lung NET from the Surveillance, Epidemiology, and End Results registry (2000-2016). Standardized incidence ratios (SIR) compared the SC incidence for NET to the US population. Multivariable Cox models examined the impact of SC on overall survival (OS) and Fine-Gray models accounting for the competing risk of death from other causes assessed the impact on disease-specific survival (DSS), with SC as a time-varying covariate.

Conference: 18th Annual ENETS Concerence (2021)

Presenting Author: Bateni S

Authors: Bateni S, Coburn N, Law C, Singh S, Myrehaug S,

Keywords: neuroendocrine tumor, secondary cancers, survival, gastrointestinal neuroendocrine tumor, pancreatic neuroendocrine tumor, pulmonary neuroendocrine tumor,