Simultanenous Duplicate Malignant Disease-Adenocarcinoma of the Colon and Disseminated Neuroendocrine Tumor

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Introduction: Fifty-nine-year old man, under examination due to weight loss, enterorrhagia, general abdominal discomfort. Endoscopy detected tumorous infiltration 20 cm from the anus, bleeding. Histology: adenocarcinoma. CT abdomen detected liver lesion. The lesion was hypervascularized, and the CT picture was atypical for metastatic adenocarcinoma. CT chest: tumor lesion in the left lower segment, metastatic LN in mediastinum. According to the CT, the picture is atypical for metastases.

Aim(s): Bronchoscopy: tumorous granulations in the region of B 10 left, histology: neuroendocrine tumor. Scintigraphy of the skelet: pathological cumulation in the ribs and chest backbone. Tumor markers within normal levels.

Materials and methods: Because of the unclear finding in the liver and patient's symptoms, resection of sigmoid tumor and liver revision was done. In the liver, multiple lesions were found and resected. Histology from sigmoid tumor: adenocarcinoma . Histology from liver metastases: neuroendocrine tumor GR 1. Octeoscan: multiple lesions of high activity found in liver, lungs, skelet. The level of CrA was 275.

Conference: 11th Annual ENETSConcerence (2014)

Presenting Author: Ostrizkova L

Authors: Ostrizkova L, Brancikova D, Mechl Z, Cerny I, Kala Z,

Keywords: duplicate malignant disease,