Somatostatin receptor expression in lung neuroendocrine tumors – An analysis of Dotatate PET scans

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Introduction: Somatostatin receptor (SSTR) expression in metastatic lung neuroendocrine (carcinoid) tumors has not been well-characterized using modern positron emission tomography (PET) imaging. Understanding the degree and uniformity of SSTR expression is important to establish the role of SSTR-targeted treatments, including peptide receptor radiotherapy (PRRT), in lung NETs.

Aim(s): Understand the degree and uniformity of SSTR expression in lung NETs.

Materials and methods: Retrospective review of medical records and imaging studies of patients with metastatic lung NETs who underwent Dotatate PET imaging (68Ga or 64Cu) at Moffitt Cancer Center since the introduction of Dotatate PET CTs in 3/2017 through 2/2022.

Conference:

Presenting Author: Al-Toubah T

Authors: Al-Toubah T, Montilla-Soler J, El-Haddad G, Strosberg J,

Keywords: PET dotatate, cu64, ga68, lung NET, SSTR Positive,