Surgical treatment of duodenopancreatic neuroendocrine tumors (pNETs) in patients with multiple endocrine neoplasia type 1 (MEN 1): a Dutch consensus statement

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Introduction: Duodenopancreatic neuroendocrine tumors (pNETs) in multiple endocrine neoplasia type 1 (MEN 1) are the most important cause of MEN 1-related death. Surgery is the only curative treatment, but controversy exists on the optimal strategy. Recent guidelines on pNETs have limited recommendations specific for MEN 1. Therefore, a Dutch multidisciplinary consensus meeting was organized.

Aim(s): To achieve a national consensus on timing and type of initial surgery for pNETs in MEN 1.

Materials and methods: (1) systematic review of literature (2) presentation of case-vignettes and discussion of different scenarios (3) presenting and discussing conclusions to come to a national consensus statement.

Conference: 7th Annual ENETSConcerence (2010)

Presenting Author:

Authors: Pieterman* C, De Herder* W, Vriens M, Van Goor H, Nieveen van Dijkum E,

Keywords: multiple endocrine neoplasia type 1, duodenopancreatic neuroendocrine tumors,, insulinoma, gastrinoma, non-functioning pancreatic neuroendocrine tumors, consensus, surgery ,