Temozolomide in Metastatic Bronchial Carcinoids

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Introduction: Metastatic bronchial carcinoids are rare neoplasms, where efforts of medical treatment thus far have been disappointing. Temozolomide has, however, shown some activity in a small prior study.

Aim(s): To perform a retrospective analysis of patients with metastatic bronchial carcinoids treated with temozolomide as monotherapy at a referral center.

Materials and methods: The medical records of all patients with metastatic bronchial carcinoid treated with temozolomide as monotherapy at our center between 2004 and 2010 (n=34; 10 typical, 14 atypical, 10 unclassified) were reviewed. Temozolomide was given at 150-200 mg/sq.m days 1-5 in a cycle of 28 d. Review of CT scans by RECIST 1.1. was possible in 23 patients.

Conference: 8th Annual ENETSConcerence (2011)

Presenting Author:

Authors: Lindholm D, Fanola I, Eriksson B, Granberg D,

Keywords: temozolomide, chemotherapy, bronchial, carcinoid, lung,