The diagnostic role of DWI-MRI for liver metastases of neuroendocrine neoplasms (NENs) in comparison with the functional imaging

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Introduction: A combination of morphological and functional imaging plays a crucial role for diagnosis, staging and therapeutic decision for neuroendocrine neoplasms (NENs). Diffusion-weighted imaging (DWI) magnetic resonance imaging (MRI) is emerging as a key imaging technique in the NEN field.

Aim(s): To evaluate the diagnostic and prognostic role of DWI-MRI in liver metastases (LM) from NENs in comparison with functional imaging with 68Ga-peptides positron emission tomography (PET)-contrast tomography (CT).

Materials and methods: This is an observational retrospective study (January 2022-September 2023) including patients with histologically proven diagnosis of gastroenteropancreatic (GEP) or lung NEN with LM evaluated with multiparametric (mp)-MRI and 68Ga-peptides PET-CT, performed less than 6 months of each other at diagnosis or follow-up. We collected clinical, pathological, and imaging data including lesions number detected at (a) mp-MRI -gold standard- (b) DWI images, (c) 68Ga-peptides PET-CT. Apparent diffusion coefficient (ADC) and standardized uptake value (SUV) were calculated on target lesions.

Conference:

Presenting Author: Sesti F

Authors: Feola T, Sesti F, Centello R, Filice A, Pirisino R,

Keywords: MRI, DWI, PET, Liver metastases,