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Towards Optimal Personalized Diet and Vitamin Supplementation in NET Patients; A Feasibility Study


Introduction: Patients with a neuroendocrine tumor (NET) often have gastro-intestinal complaints due to somatostatin analogue (SSA), tumor mass, secretion of neuroendocrine amines or treatment. This can lead to impaired absorption of critical food components such as vitamins. Serotonin producing NET patients may also have low plasma tryptophan.

Aim(s): To explore if personalized dietary advice and supplementation of deficient vitamins is feasible.

Materials and methods: Fifteen NET patients using a SSA were counseled by a dietician for a personalized dietary advice and supplementation of deficient vitamins. Feasibility was assessed by calculation of participation/dropout rate and safety. After 4 and 18 weeks, quality of life (QoL), distress, empowerment and nutrition state were assessed. Also, vitamins and tryptophan levels in blood and urine were measured.

Conference: 14th Annual ENETSConcerence (2017)

Presenting Author: de Hosson L

Authors: De Hosson L, Bouma G, Van Essen H, Sijtema B, Huitema S,

Keywords: diet, vitamin, neuroendocrine tumor, somatostatin,

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