Trans-Arterial Embolization (TAE) is the Best Locoregional Treatment Option for Patients with Liver Metastases from Neuroendocrine Tumors


Introduction: Trans-arterial embolization (TAE) and chemoembolization (TACE) have been shown to be effective in patients (pts) with liver metastases (LM) from gastroenteropancreatic neuroendocrine tumor (GEP NET). TAE and TACE goal is to reduce blood flow to the tumor resulting in ischemia and necrosi.

Aim(s): Which procedure, among TAE and TACE, represent the best option in NET pts is still debated. Criteria to predict response to TAE/TACE other than objective tumor response are not defined. This challenge represents the purpose of this retrospective investigation.

Materials and methods: Forty pts (26 M, 14 F; mean age 61 yrs) with GEP NET with LM, 16 of whom with a functioning tumor were investigated. TAE was performed in 27 and TACE in 18 pts. Contrast-enhanced CT scans were performed at baseline and then after two and six months by these procedures. Change in tumor size and degree of devascularization, as compared to the baseline evaluation, were considered.

Conference: 9th Annual ENETSConcerence (2012)

Presenting Author:

Authors: Del Prete M, Faggiano A, Marotta V, Ramundo V, Marciello F,

Keywords: TAE, TACE, NET,

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