Treatment and Prognosis of Patients with Poorly Differentiated Neuroendocrine Tumors


Introduction: Poorly differentiated neuroendocrine tumors (PDEC) represent less than 10% of all neuroendocrine tumors but have a poor prognosis.

Aim(s): To study clinical, biochemical and imaging data on prognosis and survival and to investigate survival in patients treated with chemotherapy.

Materials and methods: A retrospective study of 32 PDEC patients (19 males, 13 females, median age at diagnosis 63 years (range 35-90)) admitted at the Neuroendocrine Tumor Center at Aarhus University Hospital in the period 2000-2008. Median Ki-67 index was 45%, and higher in colon (85%, 50-98) compared to pancreas (25%, 20-40) PDEC. Data were obtained from patient files.

Conference: 8th Annual ENETSConcerence (2011)

Presenting Author:

Authors: Holt N, Villadsen G, Olesen R, Grønbæk H,

Keywords: poorly differentiated neuroendocrine tumors, PDEC, survival,

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