Treatment response and survival in 163 metastatic colorectal neuroendocrine carcinomas: A prospective cohort from the Nordic NEC registry

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Introduction: Colorectal neuroendocrine carcinoma (CR-NEC) is a rare and aggressive disease. Most cases are metastatic at diagnosis and palliative chemotherapy is the only systemic treatment option.

Aim(s): Determine the clinical and molecular characteristics, treatment response, and survival in a large prospective cohort of metastatic CR-NEC.

Materials and methods: The Nordic NEC registry (2013-2017) identified 163 CR-NEC patients receiving palliative chemotherapy. Pathology was re-evaluated according to the 2019 WHO classification.

Conference:

Presenting Author: Morken S

Authors: Morken S, Langer S, Knigge U, Hjortland G, Sundlöv A,

Keywords: neuroendocrine carcinoma, NEC, colorectal, chemotherapy,