Unresectable Mesenteric Midgut NETs: Are They a Unique Prognostic Category?

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Introduction: Patients with lymph-node positive midgut NETs (stage IIIB) represent a heterogeneous group. While some have microscopic lymph node involvement on pathological evaluation, others may develop large, desmoplastic, unresectable tumors in the root of the mesentery.

Aim(s): To assess whether unresectable lymph node metastases in the root of the mesentery represent a distinct prognostic group among patients with stage IIIB midgut NETs.

Materials and methods: Within a database of jejunal-ileal NETs seen at the Moffitt Cancer Center between 2000 and 2010, we identified patients with lymph-node involvement (stage IIIB). We then compared overall survival between resectable and unresectable lymph node metastases using log-rank analysis.

Conference: 9th Annual ENETSConcerence (2012)

Presenting Author:

Authors: Strosberg J, Weber J, Feldman M, Kvols L,

Keywords: neuroendocrine tumors, carcinoid tumor, midgut, lymph node metastases, stage III,