Vasostatin-1 Predicts Recurrence in Patients Submitted to Surgery for Nonfunctioning Pancreatic Neuroendocrine Tumors (NF-PanNET)

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Introduction: An association between preoperative Vasostatin-1 (VS-1) plasma level and pathological features of aggressiveness was previously reported in patients with surgically resected nonfunctioning (NF) PanNET.

Aim(s): To evaluate VS-1, in comparison with Chromogranin A (CgA), as predictor of disease recurrence.

Materials and methods: Patients who underwent surgery for localized NF-PanNET at San Raffaele Scientific Institute were included (n=50). VS-1 and total-CgA were measured by enzyme-linked immunosorbent assay (ELISA) on preoperative plasma samples.

Conference: 17th Annual ENETSConcerence (2020)

Presenting Author: Andreasi V

Authors: Andreasi V, Partelli S, Manzoni M, Muffatti F, Colombo B,

Keywords: pancreatic neuroendocrine tumors, biomarkers, chromogranin A, vasostatin 1, recurrence,