Well-Differentiated Neuroendocrine Lesions in Inflammatory Bowel Disease

#2172

Introduction: Whether inflammatory Bowel disease (IBD) increases the risk of developing neuroendocrine tumors (NETs) is not clear. NETs are rare in IBD, though one recent report suggests that NETs are 15 times more frequent in patients with Crohn’s disease. Besides NETs, which are discrete mass-forming lesions, microscopic neuroendocrine cell clusters or micronests (NEMs), difficult to measure, are sometimes observed in the lamina propria/muscularis mucosae of IBD patients.

Aim(s): The current study was undertaken to identify the incidence of NETs in IBD and to examine the clinical and pathologic features of NETs and NEMs in IBD.

Materials and methods: Departmental pathology archives were searched to identify cases of NETs and NEMs in patients with IBD. Cases were reviewed to investigate the pathologic features.

Conference: 15th Annual ENETSConcerence (2018)

Presenting Author: Dhall D

Authors: Dhall D, Wong M, Larson B,

Keywords: Inflammatory bowel disease, neuroendocrine tumors, neuroendocrine micronests,